Patent · US Expired

Pyrazolecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them, and method of treating

US6645985B2 · kind B2 · utility

6Cited by

2References

2Claims

0Family size

Inventors

Francis Barth · Juvignac, FR
Philippe Camus · Muret, FR
Serge Martinez · Montpellier, FR
Murielle Rinaldi · Juvignac, FR

Key dates

Filing date	Jun 7, 2002
Grant date	Nov 11, 2003
Priority date	—
Expiry date	Jun 7, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C251/80
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

N-Piperidino-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethylpyrazole -3-carboxamide and its salts and solvates are powerful antagonists of the CB1 cannabinoid receptors. They are prepared by reacting a functional derivative of 5-(4-bromophenyl)-1-(2,4-dichlorophenyl) -4-ethylpyrazole-3-carboxylic acid with 1-aminopiperidine, optionally followed by salification.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.