Method of treating hair loss using sulfonyl thyromimetic compounds
US6646005B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 21, 2002 |
| Grant date | Nov 11, 2003 |
| Priority date | — |
| Expiry date | Feb 21, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P17/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for treating hair loss using a composition including a compound having the following structure and pharmaceutically acceptable salts, hydrates, and biohydrolyzable amides, esters, and imides thereof are provided. R1 is —(CH2)n(CHNR7R8)mC(O)R9, wherein n is an integer from 1 to 3, and m is an integer from 0 to 1. R3 and R5each, independently, is chlorine, bromine, iodine and —CH3. R7 and R8 each, independently, is hydrogen or C1 to C4 alkyl. R9 is hydroxy, C1 to C4 alkoxy and —NR7R8. R31 is a hydrogen, chlorine, bromine, iodine, C1 to C4 alkyl, C4 to C6 cycloalklyl, C1 to C4 haloalkyl, C4 to C6 halocycloalkyl, or CH(R10)Ar. Ar is 5-hydroxypyrid-2-yl, 6-hydroxypyrid-3-yl, 6-hydroxypyridazin-3-yl, 6-methioxypyridazin-3-yl N-oxide or 6-hydroxypyridazin-3-yl N-oxide. R10 is hydrogen or C1 to C4 alkyl. R41 is hydroxy or C1 to C4 alkoxy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.