Adenoviral vectors for enhanced gene expression
US6649375B2 · kind B2 · utility
11Cited by
14References
106Claims
0Family size
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Key dates
| Filing date | Sep 10, 1998 |
| Grant date | Nov 18, 2003 |
| Priority date | — |
| Expiry date | Sep 10, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/804
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An adenoviral vector including at least one DNA sequence encoding a clotting factor, such as, for example, Factor VIII, or Factor IX. Such vectors may be administered to a host in an amount effective to treat hemophilia in the host. The vectors infect hepatocytes very efficiently, whereby the hepatocytes express the DNA sequence encoding the clotting factor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.