Quinoline and quinazoline compounds useful in therapy
US6649620B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 23, 2002 |
| Grant date | Nov 18, 2003 |
| Priority date | — |
| Expiry date | Sep 23, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula I, whereinR1 represents C1-4 alkoxy optionally substituted by one or more fluorine atoms;R2 represents an aryl group or a heteroaryl group, optionally substituted by C1-4 alkyl or SO2NH2;R3 represents a 4-, 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring system as a whole being optionally substituted;X represents CH or N; andL is absent, or represents a cyclic group of formula Ia,  or represents a chain of formula Ib,  and pharmaceutically acceptable salts thereof, are useful in the treatment of a variety of disorders including benign prostatic hyperplasia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.