Patent · US Expired

N-substituted 1-(lactone) isoquinolones for treating nervous disorders

US6649626B1 · kind B1 · utility

3Cited by
0References
11Claims
0Family size

Assignees

Inventors

Key dates

Filing dateAug 15, 2002
Grant dateNov 18, 2003
Priority date
Expiry dateAug 15, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention concerns compounds of general formula (I) wherein: Z represents a sulphur or oxygen atom, NH, N-alkyl or Nboc; group R′, identical or different, represent each a hydrogen atom, a OCH3 group or a OCH2O group; group R″ represents a hydrogen or a CH3 group; group X represents a carbonyl, sulphonyl or CO2 group; and group R represents an alkyl, aryl, alkenyl or aralkyl group. The invention also concerns the preparation of said compounds, pharmaceutical compositions containing them and their use for stimulating &ggr;-amino-butyric acid activity and as medicine for treating nervous disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.