Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis
US6649769B2 · kind B2 · utility
14Cited by
8References
54Claims
0Family size
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Key dates
| Filing date | Aug 21, 2002 |
| Grant date | Nov 18, 2003 |
| Priority date | — |
| Expiry date | Aug 21, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/533
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Atropisomeric energy-transfer dye compounds are disclosed. A variety of molecular biology applications utilize atropisomeric xanthene fluorescent dyes as labels for substrates such as nucleotides, nucleosides, polynucleotides, polypeptides and carbohydrates. Methods include DNA sequencing, DNA fragment analysis, PCR, SNP analysis, oligonucleotide ligation, amplification, minisequencing, and primer extension.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.