Inhaled vaccines
US6651655B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 2, 2000 |
| Grant date | Nov 25, 2003 |
| Priority date | — |
| Expiry date | May 2, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2202/30
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
In a method for creating an immune response, a vaccine is prepared in the form of a dry powder. The powder particles have an aerodynamic particle size range from 1-100 microns. A dose of powder is loaded into a dry powder inhaler. The dose is inhaled with an inspiratory flow rate of less than 60 liters per minute. A mucosal immune response is created via particles of the vaccine material depositing on the upper respiratory tract. A systemic immune response is created via particles of the vaccine material depositing into the deep lung. The vaccine material is size reduced by e.g., jet milling, into the desired range, yet vaccine potency is retained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.