Method of reducing the immunogenicity of compounds
US6652863B1 · kind B1 · utility
5Cited by
7References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 6, 1995 |
| Grant date | Nov 25, 2003 |
| Priority date | — |
| Expiry date | Jul 6, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Reduced-immunogenic fusion compounds are disclosed. The fusion compounds of the invention comprise immunogenic compounds linked to auto-antigenic sequences which render the compound less immunogenic. In addition, a method of reducing the immunogenicity of an immunogenic compound is disclosed. The method comprises linking an auto-antigenic sequence to an otherwise immunogenic compound. Recombinant nucleotide sequences encoding auto-antigenic sequences are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.