Compounds for intracellular delivery of therapeutic moieties to nerve cells
US6652864B1 · kind B1 · utility
19Cited by
9References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 21, 1998 |
| Grant date | Nov 25, 2003 |
| Priority date | — |
| Expiry date | Dec 21, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound for delivering a non-cytotoxic therapeutic moiety into nerve cells, the compound having the general formula:B—L—TMwhere:B is a binding agent capable of selectively binding to a nerve cell surface receptor and mediating absorption of the compound by the nerve cell;TM is a therapeutic moiety which has a non-cytotoxic therapeutic effect when absorbed by a nerve cell; andL is a linker coupling B to TM.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.