Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
US6652886B2 · kind B2 · utility
134Cited by
11References
27Claims
0Family size
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Key dates
| Filing date | Feb 16, 2001 |
| Grant date | Nov 25, 2003 |
| Priority date | — |
| Expiry date | Feb 16, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/906
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A biodegradable, novel cationic coopolymer comprising a a poly(alkylenimine)(PAI), a hydrophilic polymer, and a biodegradable linker, wherein the biodegradable linker covalently links the PAI and the hydrophilic polymer. The biodegradable cationic copolymers in the present invention can be used in drug delivery and are especially useful for delivery of a nucleic acid or any anionic bioactive agent to various organs and tissues after local or systemic administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.