Patent · US Expired

3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives as protein kinase inhibitors

US6653308B2 · kind B2 · utility

10Cited by
80References
40Claims
0Family size

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Inventors

Key dates

Filing dateFeb 15, 2002
Grant dateNov 25, 2003
Priority date
Expiry dateFeb 15, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.