Patent · US Expired

Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade

US6653316B1 · kind B1 · utility

10Cited by
18References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 20, 2000
Grant dateNov 25, 2003
Priority date
Expiry dateNov 20, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to substituted polycyclic aryl and heteroaryl pyrimidinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.