Transgenic mice exhibiting increased susceptibility to seizures
US6653526B2 · kind B2 · utility
2Cited by
0References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 11, 2001 |
| Grant date | Nov 25, 2003 |
| Priority date | — |
| Expiry date | Jul 11, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a ubiquitin-specific protease 16 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.