Aerosolized active agent delivery
US6655379B2 · kind B2 · utility
160Cited by
129References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 11, 1999 |
| Grant date | Dec 2, 2003 |
| Priority date | — |
| Expiry date | Mar 15, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M15/002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to methods and devices for delivering an active agent formulation to the lung of a human patient. The active agent formulation may be in dry powder form, it may be nebulized, or it may be in admixture with a propellant. The active agent formulation is delivered to a patient at an inspiratory flow rate of less than 17 liters per minute. The bioavailability of the active agent was found to increase at these flow rates when compared to inspiratory flow rates of 17 liters per minute or more.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.