Method and composition for dry eye treatment
US6656460B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 1, 2001 |
| Grant date | Dec 2, 2003 |
| Priority date | — |
| Expiry date | Dec 15, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/685
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and composition for treating a dry eye condition by topically applying to the eye surfaces an emulsion forming a tear film that acts to lubricate the eye and to inhibit evaporation therefrom. The emulsion is constituted by water in which is dispersed a mixture that includes a phospholipid, a non-polar oil, a non-toxic emulsifying agent and a polar lipid that imparts a net positive charge to the film that is distributed throughout the film, causing the film to be electrostatically attracted to the anionic surface of the eye whereby the film adheres thereto and cannot be washed away. Includable in the mixture is a non-soluble therapeutic agent, such as cyclosporin which is effective against an eye disease and is delivered to the eye by the film.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.