Patent · US Expired

Fermentative preparation process for and crystal forms of cytostatics

US6656711B2 · kind B2 · utility

1Cited by

8References

6Claims

0Family size

Assignee

Novartis AG · CH

Inventors

Hans Hofmann · Odenthal, DE
Marion Mahnke · Steinen, DE
Klaus Memmert · Lörrach, DE
Frank Petersen · Weil am Rhein, DE
Thomas Schupp · Möhlin, CH
Ernst Kusters · Sankt Goarshausen, DE
Michael Mutz · Glückstadt, DE

Key dates

Filing date	Jan 29, 2002
Grant date	Dec 2, 2003
Priority date	—
Expiry date	Mar 23, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12R2001/01
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to a new process for concentrating epothilones in culture media, a new process for the production of epothilones, a new process for separating epothilones A and B and a new strain obtained by mutagenesis for the production of epothilones, as well as aspects related thereto. New crystal forms of epothilone B are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.