Trisubstituted carbocyclic cyclophilin binding compounds and their use
US6656971B2 · kind B2 · utility
55Cited by
150References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 25, 2002 |
| Grant date | Dec 2, 2003 |
| Priority date | — |
| Expiry date | Jan 25, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one or more of the said compounds. The invention further relates to the uses of these compounds and compositions for binding CyP-type proteins, inhibiting their peptidyl-prolyl isomerase activity, and for research, development, and therapeutic applications in a variety of medical disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.