Process for preparing methylene bisphosphonic and salts
US6657076B1 · kind B1 · utility
5Cited by
2References
13Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 14, 2002 |
| Grant date | Dec 2, 2003 |
| Priority date | — |
| Expiry date | Mar 14, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/3843
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of salts of substituted or unsubstituted methylene bisphosphonic acids by hydrolysing the corresponding acid ester with hydrochloric acid, removing water from the acid azeotropically prior to addition of an amine or a base to produce the resultant salt in good yield.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.