Ray-based image analysis for biological specimens
US6658143B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 29, 2002 |
| Grant date | Dec 2, 2003 |
| Priority date | — |
| Expiry date | May 9, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30024
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Image acquisition and analysis systems and methods are provided. A ray-based approach may be used to process images for cell-based assays. Such cell-based assays may be used to evaluate drugs or other compounds or to perform other biological studies. A scanning laser microscope or other equipment may be used to gather image data from fluorescently-marked cells or other suitable specimens. The rays are radially-oriented with respect to the cell nuclei. Seed points within the nuclei may be identified. The rays may extend outward from the seed points or other suitable ray origins until the rays are terminated according to ray termination criteria. The intensity of the image data that is associated with each of the rays may be analyzed to generate various parameters. For example, a peak intensity of the image data along each ray may be identified. Statistical calculations may be performed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.