Emulsion vehicle for poorly soluble drugs
US6660286B1 · kind B1 · utility
48Cited by
32References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 24, 1999 |
| Grant date | Dec 9, 2003 |
| Priority date | — |
| Expiry date | May 24, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/915
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An emulsion of tocopherol incorporating a co-solvent and, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans by various routes is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated &agr;-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of &agr;-tocopherol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.