Patent · US Expired

Lead substances and their use as therapeutics

US6660835B1 · kind B1 · utility

6Cited by

0References

16Claims

0Family size

Assignee

Friedrich Goetz · DE

Inventors

Michael Otto · Lilburn, US
Roderich Suessmuth · Berlin, DE
Guenther-Gerhard Jung · Tübingen, DE
Friedrich Goetz · Lörrach, DE

Key dates

Filing date	Dec 24, 1998
Grant date	Dec 9, 2003
Priority date	—
Expiry date	Dec 24, 2018

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to peptides, which are useful in treating Staphylococcus infections. More particularly, the inventive peptides interfere with the regulation of the agr system of Staphylococcus species, especially S. aureus, and thereby block the formation of different virulence factors. The inventive peptides comprise at least the amino acid sequence S V X A S Y F, whereby cyclic structures of that kind of peptides are the most potent blocking reagents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.