Modified protein derived from protein kinase N
US6660837B1 · kind B1 · utility
8Cited by
0References
5Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 24, 1996 |
| Grant date | Dec 9, 2003 |
| Priority date | — |
| Expiry date | Jul 24, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/12
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A object of the present invention is to provide a peptide inhibiting tumorigenesis or metastasis. The present invention is a peptide or derivatives thereof comprising a modified amino acid sequence of Protein Kinase N having the activated Rho protein binding activity and not having protein kinase activity, and a peptide or derivatives thereof comprising a modified amino acid sequence of Protein Kinase N inhibiting the protein kinase activity of Protein Kinase N or the enhancement of the activity and not having protein kinase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.