Fixation of nucleotide derivatives to solid carrier
US6664051B1 · kind B1 · utility
3Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 3, 2000 |
| Grant date | Dec 16, 2003 |
| Priority date | — |
| Expiry date | Nov 3, 2020 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2219/00677
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A DNA chip or its analogue composed of nucleotide derivatives attached to a solid carrier is prepared by method of bringing nucleotide derivatives having a reactive group at each one terminal into contact with a solid carrier having thereon reactive groups in an aqueous phase in the presence of a transferase which is capable of producing a covalent bond by rearrangement of the reactive group of the nucleotide derivative and the reactive group of the solid carrier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.