Antivesicant compounds and methods of making and using thereof
US6664280B2 · kind B2 · utility
3Cited by
5References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 2002 |
| Grant date | Dec 16, 2003 |
| Priority date | — |
| Expiry date | Jun 17, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/89
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
As disclosed herein, the present invention provides a compound having the structural formula wherein R1, R2, R3, and R4 are each independently H, or a methyl, halo, trifluoromethyl, nitro, alkyloxy, or acyloxy group, or a pharmaceutically acceptable salt or prodrug thereof. Also disclosed are compounds, compositions, methods and kits for treating, preventing, or inhibiting injuries induced by a vesicant agent, such as bis-2-chloroethylsulfide (HD). Additionally, protectants and decontaminants are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.