Electrochemical saccharide sensor
US6664407B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 30, 2002 |
| Grant date | Dec 16, 2003 |
| Priority date | — |
| Expiry date | Apr 19, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F17/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides compounds for detecting sacchharides by electrochemistry. The compounds have a structure that includes a first boronic acid group attached by a first linker group to a first tertiary amine. The first tertiary amine is attached to a reporter group that includes an organometalic reporter moiety. A spacer group attaches the first tertiary amine to a second tertiary amine. The second tertiary amine is attached to an R group and a second linker group. The second linker group is attached to a second boronic acid group. In preferred embodiments, the compound selectively detects glucose and has a higher relative stability constant for glucose than for other saccharides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.