Oral forms of administration containing solid flupirtine with controlled release of active substance

US6667058B1 · kind B1 · utility

Assignee

• Viatris GmbH & Co. KG · DE

Inventors

• Joachim Goede · Hanau, DE
• Helmut Hettche · Dietzenbach, DE
• Helmut Momberger · Marburg, DE
• Jurgen Engel · Alzenau, DE
• Michael Lobisch · Ober-Ramstadt, DE

Key dates

• Filing date: Mar 17, 1994
• Grant date: Dec 23, 2003
• Expiry date: Feb 17, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pharmaceutical dosage units containing flupirtine or a pharmaceutically acceptable salt of flupirtine with controlled release of active substance using a delayed-action or controlled-release component. There are 0.001 to 20 parts delayed-action component for each part by weight flupirtine (calculated as the base) and the release rate of flupirtine is between 5 and 300 mg per hour. In some cases, the dosage units may also contain a rapidly releasing component of flupirtine or of one of its salts. The dosage units reduce the sedative effect of flupirtine.