Cyclobutene derivatives useful as antagonists of the motilin receptor
US6667309B2 · kind B2 · utility
8Cited by
3References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 12, 2002 |
| Grant date | Dec 23, 2003 |
| Priority date | — |
| Expiry date | Mar 12, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The compounds of formula I are useful in treating gastrointestinal disorders associated with antagonizing the motilin receptor. The compounds compete with erythromycin and motilin for the motilin receptor. In addition the compounds are antagonists of the contractile smooth muscle response to those ligands.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.