Method and system for measuring T-wave alternans by alignment of alternating median beats to a cubic spline

US6668189B2 · kind B2 · utility

Assignee

• GE Medical Systems Information Technologies, Inc. · US

Inventors

• Willi Kaiser · Glückstadt, DE
• Martin Findeis · Glückstadt, DE

Key dates

• Filing date: Oct 5, 2001
• Grant date: Dec 23, 2003
• Expiry date: Nov 23, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B5/355
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

An electrocardiogram processing technique for measuring T-wave alternans by which the alternating electrocardiogram signals are aligned to a target cubic spline. The target cubic spline is calculated on base of three isoelectric points namely a point before the P-wave, a point before the QRS-complex and a point after the T-wave. The aligned signals may then be further analyzed for variations such as T-wave alternans which are only present in alternating beats and which have diagnostic significance.