Retroviral vectors
US6669936B2 · kind B2 · utility
16Cited by
7References
75Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 25, 2001 |
| Grant date | Dec 30, 2003 |
| Priority date | — |
| Expiry date | Jul 25, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Retroviral vector production systems for producing lentivirus-based vector particles which are capable of infecting and transducing non-dividing target cells, wherein one or more of the auxiliary genes such as vpr, vif, tat, and nef in the case of HIV-1 are absent from the system. The systems and resulting retrovirus vector particles have improved safety over existing systems and vectors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.