Patent · US Expired

Host derived proteins binding HCV: medical, diagnostic and purification use

US6670114B1 · kind B1 · utility

3Cited by

3References

13Claims

0Family size

Assignee

N.V. Innogenetics · BE

Inventors

Geert Maertens · Brugge, BE
Erik Depla · Laarne, BE

Key dates

Filing date	May 5, 2000
Grant date	Dec 30, 2003
Priority date	—
Expiry date	May 5, 2020

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/4718
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The finding that the human proteins annexin V, tubulin and apolipoprotein B bind to the hepatitis C virus envelope proteins E1 and/or E2 and the usage of these human proteins to diagnose and treat an infection with hepatitis C virus are described. The usage of the latter proteins to enrich HCV envelope proteins and molecules which inhibit binding of HCV to these human proteins, as well as vaccines employing the E1 and/or E2 binding domains are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.