Patent · US Expired

Recombinant Streptomyces hygroscopicus host cells that produce 17-desmethylrapamycin

US6670168B1 · kind B1 · utility

13Cited by

6References

1Claims

0Family size

Assignee

Kosan Bioscience, Inc. · US

Inventors

Leonard Katz · Oakland, US
Lu Liu · Palo Alto, US
Loleta M. Chung · San Francisco, US

Key dates

Filing date	Oct 30, 2000
Grant date	Dec 30, 2003
Priority date	—
Expiry date	Jan 20, 2021

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P17/188
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Recombinant host cells that produce rapamycin analogues are constructed by deleting or modifying rapamycin biosynthetic gene cluster genes and are useful in the production of compounds used as antifungals, anticancers, immunosuppressants, and neurotrophins.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.