Bicyclic modulators of androgen receptor function

US6670386B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Chongqing Sun · Plainsboro, US
• Jeffrey A. Robl · Newtown, US
• Mark E. Salvati · Lawrenceville, US
• Tammy C. Wang · Lawrenceville, US
• Lawrence G. Hamann · North Grafton, US
• David J. Augeri · Princeton, US

Key dates

• Filing date: Jul 31, 2002
• Grant date: Dec 30, 2003
• Expiry date: Jul 31, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention provides compounds of the formula I wherein the substitutents are as described herein.Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia, and also provided are pharmaceutical compositions containing such compounds.