Patent · US Expired

Polypeptide and protein derivatives and process for their preparation

US6673347B1 · kind B1 · utility

13Cited by
17References
69Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 12, 1994
Grant dateJan 6, 2004
Priority date
Expiry dateMay 12, 2014

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2123/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Protein and polypeptide derivatives and their salts are claimed characterized in that a protein or polypeptide is conjugated via an intermediate grouping containing at least one radical of the formula —C(R)═N— (or —N═C(R)—) or —CH(R)—NH— (or —NH—CH(R)—), wherein R is hydrogen or a hydrocarbon residue which may be substituted, with the same or a different protein or polypeptide, with a reporter group or a cytotoxic agent as well as a process for their preparation and the novel intermediates therefor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.