Patent · US Expired

Use of Mullerian inhibiting substance for treating excess androgen states

US6673352B1 · kind B1 · utility

7Cited by
16References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 14, 2000
Grant dateJan 6, 2004
Priority date
Expiry dateSep 14, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K48/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a method of treating a condition or disease characterized by an excess of one or more androgens, the method comprising administering an effective amount of MIS protein or nucleic acid encoding MIS to a patient. The present invention also provides a method of decreasing the level of one or more androgens to a level below the normal level, the method comprising administering an effective amount of MIS protein or nucleic acid encoding MIS to a patient. The methods of the present invention are particularly well-suited for the treatment of prostatic cancer, polycystic ovarian disease, benign prostatic hypertrophy, and precocious puberty.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.