4,5,-dihydroisoxazolylakylpiperazine derivatives having selective biological activity at dopamine D3 or D4 receptor, and preparation thereof
US6673800B2 · kind B2 · utility
2Cited by
2References
5Claims
0Family size
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Key dates
| Filing date | Apr 20, 2001 |
| Grant date | Jan 6, 2004 |
| Priority date | — |
| Expiry date | Aug 17, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D261/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to 4,5-dihydroisoxazolylalkylpiperazine derivatives having selective biological activity at dopamine D3 and D4 receptors represented by the following Formula (1), and its preparation method through reductive amination reaction in the presence of reducing agent, wherein R1, R2, X and n are the same as defined in the specification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.