Patent · US Expired

Method of producing n-(4,5-bis-methanesulfonyl-2-methyl-benzoyl)-guanidine, the hydrochloride thereof

US6673968B1 · kind B1 · utility

3Cited by

2References

5Claims

0Family size

Assignee

MERCK PATENT GESELLSCHAFT MIT BESHRANK TER HAFTUNG · DE

Inventors

Rolf Gericke · Seeheim-Jugenheim, DE
Manfred Baumgarth
Hans-Markus Bender · Birkenfeld, DE
Bernhard Ladstetter · Bad Aibling, DE

Key dates

Filing date	Sep 4, 2002
Grant date	Jan 6, 2004
Priority date	—
Expiry date	Sep 4, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C317/44
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to an NHE-1 selective Na+/H+ antiporter inhibitor N-(4,5-bismethanesulfonyl-2-methylbenzoyl)guanidine, hydrochloride, to its hydrochloride hydrate, and to a process for the preparation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.