Perfluoroalkyl-containing complexes with polar radicals, process for their production and their use

US6676928B2 · kind B2 · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Johannes Platzek · Berlin, DE
• Peter Mareski · Berlin, DE
• Ulrich Niedballa · Berlin, DE
• Bernd Raduechel · Berlin, DE
• Hanns-Joachim Weinmann · Berlin, DE
• Bernd Misselwitz · Berlin, DE

Key dates

• Filing date: Aug 10, 2001
• Grant date: Jan 13, 2004
• Expiry date: Aug 10, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D257/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Perfluoroalkyl-containing complexes with polar radicals of general formula I(K)1-G-(Z-Rf)m(R)p  (I) in which R means the polar radical, Rf means a perfluorinated carbon chain, K is a metal complex, and Z represents a linker group,are suitable for intravenous lymphography, for tumor diagnosis and for infarction and necrosis imaging.