Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines

US6676942B1 · kind B1 · utility

Assignees

• SmithKline Beecham Biologicals S.A. · BE
• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US
• DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS · DE

Inventors

• Yves Lobet · Rixensart, BE
• Markus Simon · Buckenhof, DE
• Ulrich E. Schaible · Freiberg, DE
• Reinhard Wallich · Heidelberg, DE
• Michael Kramer · Freiberg, DE

Key dates

• Filing date: Apr 1, 1999
• Grant date: Jan 13, 2004
• Expiry date: Apr 1, 2019

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention related to novel Borrelia, and OspA antigens derived therefrom. These antigens show little homology with know OspA's and are therefore useful as vaccine and diagnostic reagents. Multicomponent vaccines based on OspA's from different Borrelia groups are also disclosed.