Enteric coated formulation for bisphosphonic acids and salts thereof
US6676965B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 26, 2000 |
| Grant date | Jan 13, 2004 |
| Priority date | — |
| Expiry date | Sep 26, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2081
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions, processes for preparing the compositions and methods of using the composition are provided. The pharmaceutical composition comprises an inert core surrounded by an active coating containing one or more bisphosphonic acids or salts thereof, a seal coating surrounding the active coating and an enteric coating surrounding the seal coating. Alendronic acid and alendronate sodium trihydrate are the preferred active ingredients. The composition may be provided in the form of pellets in a capsule or Peltabs. The invention further provides methods for the treatment of disorders caused by the abnormal dissolution or deposition of calcium salts using the inventive compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.