Ret ligand (RetL) for stimulating neutral and renal growth
US6677135B1 · kind B1 · utility
15Cited by
5References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1998 |
| Grant date | Jan 13, 2004 |
| Priority date | — |
| Expiry date | Nov 6, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Nucleotide and amino acid sequences are provided for compounds which promote tissue growth, as well as methods for modulating tissue growth, for imaging tissues and organs, and for treating patients. Isolated nucleic acid and amino acid sequences for Ret ligands are disclosed. Ret ligands encoded by the isolated nucleic acid sequences of the invention have a hydrophobic N-terminal signal sequence, a hydrophobic C-terminal sequence and a phosphatidylinositol glycan linkage motif. Vectors and host cells that include Ret ligands encoded by the isolated nucleic acid sequences of the invention are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.