Ring-expanded nucleosides and nucleotides
US6677310B1 · kind B1 · utility
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2References
31Claims
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Key dates
| Filing date | Apr 21, 1999 |
| Grant date | Jan 13, 2004 |
| Priority date | — |
| Expiry date | Apr 21, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/7056
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions comprising analogues of purine nucleosides containing a ring-expanded (“fat”) heterocyclic ring, in place of purine, and an unmodified or modified sugar residue, pharmaceutically acceptable derivatives of such compositions, as well as methods of use thereof. In particular, these compositions may be utilized in the treatment of certain cancers, bacterial, fungal, parasitic, and viral infections, including, but not limited to, Acquired Immunodeficiency Syndrome (AIDS), hepatitis, Epstein-Barr and cytomegalovirus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.