Patent · US Expired

Pharmaceutically active compounds

US6677335B1 · kind B1 · utility

4Cited by
14References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 6, 2000
Grant dateJan 13, 2004
Priority date
Expiry dateOct 6, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of the formula (I): wherein R1, R2, R4 and R13 are as defined or a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or pro-drug thereof: are potent and selective inhibitors of type 5 cyclic guanosine 3′,5′-monophosphate phosphodiesterase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.