Methods, compositions and articles for reducing or preventing the effects of inflammation
US6677366B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Aug 13, 2001 |
| Grant date | Jan 13, 2004 |
| Priority date | — |
| Expiry date | Nov 30, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for reducing or preventing the effects of inflammation arising from injured tissue, which method comprises the steps of:a. bringing the injured tissue, or pre-injured tissue, into contact with a photosensitizing agent capable of penetrating into the tissue, resulting in the desired degree of biodistribution in less than one hour; andb. exposing the tissue thus contacted to light having a wavelength absorbed by the photosensitizing agent for a time sufficient to reduce or prevent inflammation in the exposed tissue, but not so long as to cause necrosis or erythema of the exposed tissue,or a pharmaceutical composition or an article for reducing or preventing the effects of inflammation arising from injured tissue.The composition comprises:a. from about 1 &mgr;g/mL to about 2 mg/mL of a photosensitizing agent capable of penetrating into the injured tissue, or pre-injured tissue, resulting in the desired degree of biodistribution less than one hour; andb. a pharmaceutically acceptable carrier.The article comprises:a. a photosensitizing agent capable of penetrating into the injured tissue, or pre-injured tissue, resulting in the desired degree of biodistribution in less than one…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.