P2X7 receptor-deficient mice and uses thereof
US6677501B2 · kind B2 · utility
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1References
6Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 6, 2001 |
| Grant date | Jan 13, 2004 |
| Priority date | — |
| Expiry date | Jun 6, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0368
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides non-human, genetically-modified mammals and genetically modified animals cells having a functionally disrupted P2×7 receptor gene. Also provided are methods for producing genetically modified mice in which one or both P2×7R alleles have been functionally inactivated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.