Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
US6678558B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 23, 2000 |
| Grant date | Jan 13, 2004 |
| Priority date | — |
| Expiry date | Mar 23, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/306
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for delivery of an agent to a cell using electroporation is disclosed. The method includes positioning a first electrode and a second electrode such that an electrical signal passed between the first electrode and the second electrode passes through the cell. The method also includes passing an electrical signal between the first electrode and the second electrode, the electrical signal having a frequency greater than about 10 kHz. In one embodiment of the method, the electrical signal has a bipolar waveform. In another embodiment of the method, the electrodes are positioned at a treatment site, e.g., a tumor, for in vivo delivery of an agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.