Patent · US Expired

Low-substituted hydroxypropyl cellulose and process for manufacturing the same

US6680069B1 · kind B1 · utility

6Cited by
10References
20Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 6, 2000
Grant dateJan 20, 2004
Priority date
Expiry dateMay 2, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08B11/08
  • WIPO fieldMacromolecular chemistry, polymers
  • WIPO sectorChemistry

Abstract

Processes for manufacturing a low-substituted hydroxypropyl cellulose are described that include dipping pulp into an alkaline solution to prepare an alkali cellulose, reacting the alkali cellulose with a hydroxypropylating agent to yield a product in a complete dissolution state, dissolving completely the product in an aqueous medium to provide a product in a complete dissolution state, neutralizing with an acid to yield a precipitate, washing, drying, and pulverizing to yield a powder having a volume-average particle diameter of less than 25 microns which is determined by a dry laser diffraction method, a loose bulk density of 0.29 g/ml or more and less than 0.40 g/ml, and a tapped bulk density of 0.55 g/ml or more. Low-substituted hydroxypropyl celluloses are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.