Passive immunization against clostridium difficile disease
US6680168B2 · kind B2 · utility
52Cited by
7References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 22, 2001 |
| Grant date | Jan 20, 2004 |
| Priority date | — |
| Expiry date | Mar 22, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile toxin-neutralizing polyclonal immune globulin, C. difficile toxoids, or combinations thereof. Also provided by the invention are C. difficile toxoids, C. difficile toxin-neutralizing polyclonal immune globulin, and methods of identifying subjects that produce C. difficile toxin-neutralizing polyclonal immune globulin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.