Method of unsupervised cell nuclei segmentation
US6681035B1 · kind B1 · utility
12Cited by
6References
15Claims
0Family size
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Key dates
| Filing date | Sep 27, 2000 |
| Grant date | Jan 20, 2004 |
| Priority date | — |
| Expiry date | Sep 27, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30024
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A method of segmentation of cell nuclei is described that uses an active contours approach based on a Viterbi search algorithm. Also disclosed is an initialisation technique that maximises the probability of a correct segmentation. The invention also includes a method to classify cell nuclei according to the difficulty of correct segmentation. Nuclei that are difficult to segment can be rejected to minimise the probability of false positives. The probability of false positives can be driven close to 0%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.