Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same
US6682729B1 · kind B1 · utility
27Cited by
4References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 19, 1999 |
| Grant date | Jan 27, 2004 |
| Priority date | — |
| Expiry date | Oct 19, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for introducing and expressing genes in animal cells is disclosed comprising infecting the animal cells with live invasive bacteria, wherein the bacteria contain a eukaryotic expression cassette encoding the gene. The gene may encode, e.g., a vaccine antigen, a therapeutic agent, an immunoregulatory agent or an anti-sense RNA or a catalytic RNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.