Ligand based solution assay for low concentration analytes
US6682903B2 · kind B2 · utility
9Cited by
16References
22Claims
0Family size
Inventor
Key dates
| Filing date | Oct 12, 2001 |
| Grant date | Jan 27, 2004 |
| Priority date | — |
| Expiry date | Jan 24, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/914
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides an assay for an analyte in solution. The assay relies, in part, on associating two catalytic activities in close proximity to each other (e.g., by conjugating each enzyme to a ligand that binds the analyte) and providing substrates that produce a colored product only when both activities are bound to the same molecule in solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.